New virtual screening strategy identifies existing drug that inhibits COVID-19 virus: In lab experiments, pralatrexate outperforms remdesivir against SARS-CoV-2

A novel computational drug screening strategy combined with lab experiments suggest that pralatrexate, a chemotherapy medication originally developed to treat lymphoma, could potentially be repurposed […]

Infant and child health are improved but the prevalence of stunting was not reduced by a combined nutrition and education program in Malawi

Childhood stunting remains a major challenge, especially in low- to middle-income countries. Even in those countries where the percentage of stunted children has gone down, […]

Discovery boosts theory that life on Earth arose from RNA-DNA mix: Newly described chemical reaction could have assembled DNA building blocks before life forms and their enzymes existed

DNA illustration (stock image). Credit: © BillionPhotos.com / stock.adobe.com Chemists at Scripps Research have made a discovery that supports a surprising new view of how […]

New class of antibiotics active against a wide range of bacteria: Dual-acting immuno-antibiotics block an essential pathway in bacteria and activate the adaptive immune response

Bacteria illustration (stock image). Credit: © k_e_n / stock.adobe.com Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing […]